SAMe (S-Adenosylmethionine) - 60 caps by Pure Encapsulations

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Regular Price: $61.30

Special Price: $33.71

Availability: In stock


Quick Overview

*Provides 200 mg per capsule of enhanced stability form SAMe.

Manufactured using a solvent-free manufacturing process.

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√ Functions as a donor of methyl groups in over 100 different reactions catalyzed by methyltransferase enzymes, as well as a precursor molecule for glutathione and polyamine synthesis*

√ Supports positive mood and cognitive function*

  • In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood*
  • Promotes healthy protein turnover to support healthy CNS function*
  • Maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity*
  • Supports neurotransmitter monoamine synthesis and function, including dopamine and serotonin, through SAMe-dependent methylation reactions*

√ Promotes liver function by supporting glutathione production*

  • Clinical trials indicate that SAMe administration enhances glutathione production in hepatic tissue and red blood cells*


√ Enhances joint comfort by supporting proteoglycan synthesis, as well as helping to stabilize and protect proteoglycans*

  • In a 16-week randomized, double-blind, placebo-controlled trial involving 56 subjects, SAMe offered statistically significant support for joint comfort*


√ Maintains healthy cell growth and cytokine balance by supporting healthy polyamine production*

*Provides 200 mg SAMe per capsule to support positive mood, cell membrane fluidity, neurotransmitter synthesis, glutathione production, joint comfort and healthy cell growth.




No statements or information on this site have been evaluated by the Food and Drug Administration. No products are intended to diagnose, treat, cure or prevent any disease.

Supplemental Facts

Amount Per Serving

each vegetarian capsule contains:

  • SAMe (S-adenosylmethionine)200 mg.
    • (from S-adenosyl-L-methionine disulphate tosylate)
  • other ingredients: hypoallergenic plant fiber (cellulose), calcium oxide, ascorbyl palmitate, calcium chloride, vegetarian capsule (cellulose, gellan gum, water)

Consult your health professional before use if you are pregnant or nursing, taking anti-depressant medication or if you have bipolar disorder.
Store Sealed in a Cool Dry Area.

Pure Encapsulations recommends 1–2 capsules daily, in divided doses, between meals, or as directed by your health care practitioner.

This product requires refrigeration.